Author: Theresa Rothenbücher

  • Biocomputing

    Biocomputing

    Biocomputing Science Fiction Coming to Life As our world becomes increasingly digital, our energy consumption keeps climbing. Quantum computing might help us keep up with growing computational needs, but it won’t solve the energy problem. Add to that the immense challenge of storing all the data we generate every day, and it’s clear: we need…

  • De-Extinction or Deception? What the Dire Wolf Saga Teaches Us

    Yesterday Nature published an article, which beautifully depicts the fight between scientists, that broke loose when Colossal Biosciences announced their claim of having “de-extinct the dire wolf” earlier this spring. Even non-scientists must have realised by now that something must be off. A healthy debate is important for science and it´s in the job description…

  • Summer update! ☀️

    I am living now on an old farm in the woods of Dalsland (Sweden).One amazing thing about Sweden is that you can live in a forest and still have the fastest internet connection. So I am perfectly able to work. 😊 Here is a sneak peek of some things I currently work on: 1) Supporting…

  • Biotech isn´t optional, it´s foundational!

    Are you an investor who avoids biotech??This is what your life most likely looks like! 😉(Spoiler: It’s bleak. And a bit smelly.) 07:00 – Wake-up.No coffee: the beans got wiped out by a fungus last year.No oat milk: There were enzymes used to make it.You settle for tap water and existential dread. 07:10 – Bathroom…

  • Every dollar, euro, or krona invested in fairytales is one not invested in science that could actually change something

    In a time when bold claims get rewarded and facts are increasingly optional, we need to be more careful, especially if we care about impact. 💚Hype stories like the recent dire wolf “de-extinction” are a clear confirmation of why my work is so necessary. Every dollar, euro, or krona invested in hyped fairytales is one…

  • Longevity

    Longevity

    Interview: Dr. Isabelle Schiffer on the real science and potential of longevity When I first heard about longevity, my gut reaction was: “Do we really need to help rich people live even longer—and give them more time to worsen their climate impact?” If your thoughts are in a similar direction, you should absolutely read on…

  • Are you relying on your co-investors to do the due diligence?

    “𝗪𝗲 𝗿𝗲𝗹𝗶𝗲𝗱 𝗼𝗻 𝗼𝘂𝗿 𝗰𝗼-𝗶𝗻𝘃𝗲𝘀𝘁𝗼𝗿𝘀 𝘁𝗼 𝗱𝗼 𝘁𝗵𝗲 𝘁𝗲𝗰𝗵𝗻𝗶𝗰𝗮𝗹 𝗱𝘂𝗲 𝗱𝗶𝗹𝗶𝗴𝗲𝗻𝗰𝗲.”It’s something I hear far too often in intro calls. And almost always, it´s followed by a regretful pause. Several VC firms have told me they’re now working to 𝗯𝘂𝗶𝗹𝗱 𝘁𝗵𝗲𝗶𝗿 𝗼𝘄𝗻 𝗲𝘅𝗽𝗲𝗿𝘁 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀 after having poor experiences relying on others to assess the scientific and technical…

  • Quick comment on the revival of the Dire Wolf

    Our time works with hype and media stunts. But what is actually behind the dire wolf story? Ancient DNA can be recovered only in bits and pieces with most of the information gone. If you are highly skilled and lucky, you will be able to obtain some genes that you can work with and use…

  • Trust is the best client feedback.

    Last week, I wrapped up a technology evaluation project for a VC firm. Their feedback: “𝘠𝘰𝘶𝘳 𝘸𝘰𝘳𝘬 𝘸𝘢𝘴 𝘱𝘪𝘷𝘰𝘵𝘢𝘭 𝘪𝘯 𝘶𝘯𝘥𝘦𝘳𝘴𝘵𝘢𝘯𝘥𝘪𝘯𝘨 𝘵𝘩𝘦 𝘴𝘤𝘪𝘦𝘯𝘵𝘪𝘧𝘪𝘤 𝘮𝘪𝘭𝘦𝘴𝘵𝘰𝘯𝘦𝘴, 𝘸𝘩𝘪𝘤𝘩 𝘩𝘦𝘭𝘱𝘦𝘥 𝘶𝘴 𝘵𝘰 𝘥𝘦𝘵𝘦𝘳𝘮𝘪𝘯𝘦 𝘩𝘰𝘸 𝘮𝘶𝘤𝘩 𝘮𝘰𝘯𝘦𝘺 𝘸𝘢𝘴 𝘳𝘦𝘲𝘶𝘪𝘳𝘦𝘥 𝘵𝘰 𝘨𝘦𝘵 𝘵𝘰 𝘴𝘦𝘳𝘪𝘦𝘴 𝘈 𝘢𝘯𝘥 𝘸𝘩𝘢𝘵 𝘵𝘩𝘦 𝘳𝘪𝘴𝘬/𝘳𝘦𝘸𝘢𝘳𝘥 𝘱𝘳𝘰𝘧𝘪𝘭𝘦 𝘭𝘰𝘰𝘬𝘴 𝘭𝘪𝘬𝘦 𝘢𝘵 𝘵𝘩𝘪𝘴 𝘵𝘪𝘮𝘦.” Happy clients, happy Theresa! 😊 It´s…

  • Investing in Half a Bridge Won´t Get You Across

    One of the most common questions investors ask me:“𝗖𝗮𝗻 𝘁𝗵𝗶𝘀 𝘀𝘁𝗮𝗿𝘁𝘂𝗽 𝗿𝗲𝗮𝗰𝗵 𝗶𝘁𝘀 𝗴𝗼𝗮𝗹𝘀 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝗳𝘂𝗻𝗱𝗶𝗻𝗴 𝘁𝗵𝗲𝘆’𝗿𝗲 𝗮𝘀𝗸𝗶𝗻𝗴 𝗳𝗼𝗿?” While it’s tempting to just crunch numbers (capex, burn rate, cost factors), I’ve found that 𝗮𝗻𝗮𝗹𝘆𝘇𝗶𝗻𝗴 𝘁𝗵𝗲 𝘁𝗶𝗺𝗲𝗹𝗶𝗻𝗲 𝗶𝘀 𝗷𝘂𝘀𝘁 𝗮𝘀 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝘁: 🧪 Even in the age of AI, 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗽𝗿𝗼𝗴𝗿𝗲𝘀𝘀 𝗶𝘀 𝘀𝘁𝗶𝗹𝗹 𝘁𝗿𝗶𝗮𝗹 𝗮𝗻𝗱…